Acute Kidney Injury Hospitalizations Increased 2000 to 2014

AKI hospitalizations were 4 times more likely among patients with diabetes.

Sucroferric Oxyhydroxide Improves Phosphorus Control in PD

In addition, average phosphate binder pill burden decreased by more than half.

Too Few Women with Diabetes Receive Recommended Preconception Counseling

Not enough women of childbearing age who have diabetes are receiving the preconception counseling recommended by the American Diabetes Association (ADA), a new study suggests. The findings will be presented in a poster on Saturday at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.

Low-calorie sweeteners may promote metabolic syndrome

New research now suggests that low-calorie sweeteners may actually help to increase fat formulation and lead to metabolic syndrome.


In a study of Black Americans who participated in focus group sessions, certain participant factors—such as knowledge of kidney disease and spiritual and cultural influences—and logistical factors—such as convenience and awareness of scheduling—were identified as barriers that may prevent Black Americans from being screened for kidney disease. Black Americans are at increased risk of developing chronic kidney disease and kidney failure.

Preeclampsia screening method found superior to current tests

New research highlights a more accurate way to screen for preeclampsia in pregnant women than currently recommended methods.

Many patients show signs of chronic kidney disease before diabetes diagnosis

Many patients who will later be diagnosed with diabetes show signs of chronic kidney disease even before their diabetes diagnosis, according to a new study. The researchers looked at data on more than 36,000 veterans who were diagnosed with diabetes between 2003 and 2013.

Anticoagulation Therapy May Prevent CV Events, Worsen Anemia in CKD

In a study, use of anticoagulants was associated with 85% fewer atherosclerotic events.

Pregnant Stone Formers Have Higher Risk for Gestational Diabetes

Pregnant women with vs without a history of nephrolithiasis are more likely to experience gestational diabetes and preeclampsia.

Calcitriol Found Not to Improve Hepcidin Levels in CKD

In a trial, oral calcitriol of 0.5 mcg daily did not reduce hepcidin levels in patients with stage 3 to 4 CKD.

TMVR Benefits Hold Firm in Post-Market Registry (CME/CE)

(MedPage Today) -- Do data point to a future 'transcatheter toolbox' for mitral disease?

Multivessel PCI Not Best in Cardiogenic Shock

(MedPage Today) -- Trial data show mortality disadvantage versus treating culprit lesions only

ASN 2017: The Future of Personalized Nephrology

(MedPage Today) -- Tissue engineering, drug discovery challenges among highlight topics

10 Questions to Challenge Your Medical News Savvy

(MedPage Today) -- Weekly News Quiz: October 20-26

Surgical Weight Loss; Low hs-cTNT Still Risky; VAD Before Pediatric Transplant

(MedPage Today) -- Cardiovascular Daily wraps up the top cardiology news of the week

EndoBreak: T1D and Vitamin D; VA's T2D Guideline; Oral Acromegaly Drug

(MedPage Today) -- News and commentary from the endocrinology world

For SAVR, Afternoon Tops Morning for Surgical Safety (CME/CE)

(MedPage Today) -- Circadian genes appear to interact with ischemia-reperfusion injury effects

Robotic-Assisted Surgery Adds Time, Costs Without Affecting Outcomes (CME/CE)

(MedPage Today) -- No improvements compared with laparoscopic procedures in kidney removal and rectal cancer

RAS Blockade After TAVI Tied to Better Outcomes (CME/CE)

(MedPage Today) -- Patients with severe aortic stenosis see reduced all-cause mortality

Borderline Pulmonary Hypertension Tied to Mortality Risk

(MedPage Today) -- Small increases in pressure might signal left heart failure, not early PAH

How much fiber is too much?

Eating too much fiber can cause bloating, gas, and constipation. Find out how much fiber is too much and how to relieve symptoms in this article.

What causes black specks in stool?

Black specks in stool can come from diet or something more serious, such as liver problems. Read about causes, symptoms, and when to see a doctor.

When is the best time to drink water?

Drinking water at any time of day helps someone to rehydrate. However, if they drink it at certain times of the day, there may be other consequences.

Why does my urine smell sweet?

Sweet-smelling urine may be caused by diet, diabetes, or maple syrup urine disease. Learn why urine may smell sweet, treatments, and when to see a doctor.

What causes Bence Jones protein in urine?

Learn about the Bence Jones protein urine test that is used to help diagnose multiple myeloma. What can you expect from the test and the results?

What happens if you have prostate surgery?

Treatment for benign prostate conditions, such as hyperplasia, can have many complications and an extensive recovery time. Learn more about it here.

Why might urination happen during intercourse?

Learn about why people might urinate during sex. This article examines the causes, treatment options, and lifestyle changes that could help.

What can you do about mucus in urine?

A look at mucus in urine, which is usually a symptom of an underlying condition. Included is detail on when to see a doctor and signs of bladder cancer.

Coping with urinary incontinence

Regardless of whether you are a man or woman, in your teens or senior years, we have found the best strategies to help you cope with urinary incontinence.

Urinary hesitancy: Causes in men and women

Urinary hesitation is when a person has trouble starting or maintaining a urine stream. Learn about the common causes in men and women.


Could grilling your meat raise blood pressure?

Researchers suggest that regular consumption of grilled or barbecued meat or fish could raise the risk of developing high blood pressure.

Low-calorie sweeteners may promote metabolic syndrome

New research now suggests that low-calorie sweeteners may actually help to increase fat formulation and lead to metabolic syndrome.

What is a left atrial enlargement?

Left atrial enlargement is linked to several conditions, including atrial fibrillation and heart failure. Learn more about the causes and treatment.

Death risk increased with two blood pressure drugs

Researchers reveal that two classes of medication used to treat hypertension could raise blood pressure variability, which may increase the risk of death.

Salt causes hypertension, but can fruits and veg save the day?

Put the salt down, because no matter how healthful your diet is, researchers found that consuming too much salt still increases blood pressure.

Common blood pressure drug may prevent type 1 diabetes

Researchers reveal that methyldopa — a drug commonly used to lower blood pressure — could also be used for the prevention and treatment of type 1 diabetes.

What you should know about white coat syndrome

White coat syndrome is a condition where a person’s blood pressure rises due to being around doctors. Included is detail on diagnosis and complications.

What you should know about anuria

A look at anuria, a condition when the kidneys stop production of urine. Included is detail on diagnosis and the potential treatment options.

What are the health benefits of celeriac?

In this article, we take a look at some of the health benefits of celeriac, along with nutritional information and some recipe suggestions.

What is an intracerebral hemorrhage?

Intracerebral hemorrhage happens when blood suddenly leaks in the brain. It is a potentially life-threatening emergency. Learn more about the risk factors.


Renal Disease and Electrolyte Course, Aspen, CO; July 23-27, 2018

University of Colorado: Registration: To register visit or contact Pam Welker at (303)724-3551 or at

USRDS Annual Report 2017

USRDS: US Renal Data System 2017 Annual Data Report: Epidemiology of Kidney Disease in the United States

In ICU, Ringer's lactate also better than saline.

NEJM: Conclusions: Among critically ill adults, the use of balanced crystalloids for intravenous fluid administration resulted in a lower rate of the composite outcome of death from any cause, new renal-replacement therapy, or persistent renal dysfunction than the use of saline.

Ringer's lactate causes less kidney injury than saline.

NEJM: Balanced crystalloids resulted in a lower incidence of major adverse kidney events within 30 days than saline (4.7% vs. 5.6%; adjusted odds ratio, 0.82; 95% CI, 0.70 to 0.95; P=0.01).

Lp(a) in the news in the New York Times

NY Times (Anahad O'Connor): “Only a small percentage of physicians know about this,” she said. “The biggest challenge for patients is finding knowledgeable physicians who know about this and can help them.”

Inhibitors of NMMT reduce obesity by increasing fat cell metabolism.

Biochem Pharmacol (Neelakantan et al): Research scientists at the University of Texas Medical Branch (UTMB) at Galveston say they developed a promising new drug that curbs obesity without dieting and, based upon preliminary study findings, they may be on their way to unleashing a breakthrough for the millions who struggle with their weight. "Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels. Notably, administration of NNMT inhibitors did not impact total food intake nor produce any observable adverse effects."

J-curve in BP studies is an artifact - similar to dose targeting bias in HEMO.

Circulation (Kalkman et al): Conclusions: Low on-treatment SBP levels are associated with increased cardiovascular events and all-cause mortality. This association is independent of the attained blood pressure level because the J curve aligns with the SBP target. Our results suggest that the benefit or risk associated with intensive blood pressure–lowering treatment can be established only via randomized clinical trials.

Toxic algae now a nationwide threat.

AP: MONROE, Mich. (AP) — Competing in a bass fishing tournament two years ago, Todd Steele cast his rod from his 21-foot motorboat — unaware that he was being poisoned. A thick, green scum coated western Lake Erie. And Steele, a semipro angler, was sickened by it.

HDCN server move still in progress

We are still in the process of moving our sever. The CME and CEU certificates don't yet work, so please hold off in taking any tests on the site. The old audio files from ASN and other meetings should work now. Suggest you use VLC player to access them -- even the old Windows Media player files as well as the Real Media files open well using this player. Get the VLC player at

HDCN moving its registration and CME server

We are in the process of moving our registration and CME server, and all emails related to this server. There may be problems for the next few days until this server move is finished.

University of Maryland School of Medicine experts lead trial on avian flu vaccine

(University of Maryland School of Medicine) Vaccine experts at the University of Maryland School of Medicine have begun multiple clinical trials of vaccines designed to protect against H7N9, an avian influenza virus that was first reported in humans in 2013 in China.

Why hospital staff sympathize with patients who self-discharge

(Lancaster University) Patients who discharge themselves from hospital should be viewed more positively say researchers, who discovered sympathy for their decision among hospital staff.Approximately 2 percent to 3 percent of patients discharge themselves from hospital against medical advice each year in the UK and US, with the numbers increasing each year.Many people who self discharge return to hospital, with readmissions costing £300 million in the UK and $2.6 billion in the US.

Nutrient-deficient diet a key Type 2 diabetes contributor for South Asians living in US

(UT Southwestern Medical Center) Less nutritious dietary choices made by South Asians living in developed countries like the US are a key contributor to the group's rising rate of Type 2 diabetes, UT Southwestern researchers report.

NIH scientists say advanced vaccines could limit future outbreaks

(NIH/National Institute of Allergy and Infectious Diseases) Novel vaccine technologies are critical to improving the public health response to infectious disease threats that continually emerge and re-emerge, according to scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. In a perspective in The Journal of the American Medical Association, the experts highlight innovations that could significantly shorten the typical decades-long vaccine development timeline.

Military surgeons report 'alarming frequency' of bench press injuries

(Loyola University Health System) A new study has found that serious chest muscle injuries are occurring with 'alarming frequency' among deployed service members who lift weights. The injuries -- tears of the pectoralis major tendon -- occurred while doing bench press weight training. The injuries then required surgical repair and six months recovery.

New group promotes artificial intelligence, robotics, automation in healthcare

(Mary Ann Liebert, Inc./Genetic Engineering News) Antiquated approaches and resistance to change hampers patient access to quality care and inflates costs according to a new organization promoting the use of artificial intelligence and related technologies in healthcare.

University Hospitals team performs first transcatheter mitral valve replacement in Ohio

(University Hospitals Cleveland Medical Center) University Hospitals Harrington Heart & Vascular Institute officially opened the APOLLO trial today implanting the Intrepid transcatheter mitral valve replacement system on the first patient involved in the study.

Physical disability boosts parenting effort, beetles study shows

(University of Edinburgh) Animals that carry a physical impediment can work harder to rear their young as a result, an insect study has shown. They may behave this way in case they are not able to reproduce again, scientists suggest.

Soybean genomes unmasked

(University of Missouri-Columbia) Having a map of soybean genes is key for breeders, who work to develop varieties that farmers can use to help battle diseases and other environmental factors. For nearly a decade, only one soybean cultivar -- 'Williams 82' -- had been sequenced, but MU scientists led by Henry Nguyen now have succeeded in mapping two more, giving breeders access to a broader array of soybean genes.

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

(University of Chicago Medical Center) A University of Chicago based research team has begun to unravel the role of RNA epigenetics and chromatin structure in the regulation of 5-azacytidine, a DNA hypomethylating agent in certain leukemias. The results could lead to novel strategies and biomarkers that could reduce the risk of drug resistance.